Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge

Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma is a rare variety of cutaneous lymphoma. This subtype has an aggressive and quickly progressive clinical course with a survival time of 32 months from the commencement of skin lesions. This article describes a probable case o...

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Autores principales: Velarde Loya, Marcela, Millan Reza, Monica G, Olaya Cordova, Mariana, Chavéz López, Zaira D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467331/
https://www.ncbi.nlm.nih.gov/pubmed/37654908
http://dx.doi.org/10.7759/cureus.44375
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author Velarde Loya, Marcela
Millan Reza, Monica G
Olaya Cordova, Mariana
Chavéz López, Zaira D
author_facet Velarde Loya, Marcela
Millan Reza, Monica G
Olaya Cordova, Mariana
Chavéz López, Zaira D
author_sort Velarde Loya, Marcela
collection PubMed
description Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma is a rare variety of cutaneous lymphoma. This subtype has an aggressive and quickly progressive clinical course with a survival time of 32 months from the commencement of skin lesions. This article describes a probable case of primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma in a 63-year-old female, which manifested as diffuse non-pruritic erythematous plaques and nodules. The diagnosis of this possible entity was aided by the histopathological and immunohistochemical findings, while immunohistochemistry for T-cell receptor (TCR) gamma/delta could not be done.
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spelling pubmed-104673312023-08-31 Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge Velarde Loya, Marcela Millan Reza, Monica G Olaya Cordova, Mariana Chavéz López, Zaira D Cureus Dermatology Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma is a rare variety of cutaneous lymphoma. This subtype has an aggressive and quickly progressive clinical course with a survival time of 32 months from the commencement of skin lesions. This article describes a probable case of primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma in a 63-year-old female, which manifested as diffuse non-pruritic erythematous plaques and nodules. The diagnosis of this possible entity was aided by the histopathological and immunohistochemical findings, while immunohistochemistry for T-cell receptor (TCR) gamma/delta could not be done. Cureus 2023-08-30 /pmc/articles/PMC10467331/ /pubmed/37654908 http://dx.doi.org/10.7759/cureus.44375 Text en Copyright © 2023, Velarde Loya et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Velarde Loya, Marcela
Millan Reza, Monica G
Olaya Cordova, Mariana
Chavéz López, Zaira D
Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge
title Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge
title_full Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge
title_fullStr Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge
title_full_unstemmed Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge
title_short Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge
title_sort probable primary cutaneous cd8+ aggressive epidermotropic cytotoxic t-cell lymphoma: a case report of a diagnostic challenge
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467331/
https://www.ncbi.nlm.nih.gov/pubmed/37654908
http://dx.doi.org/10.7759/cureus.44375
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