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Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging

Theranostic agents are promising due to their ability to diagnose, treat and monitor different types of cancer using a variety of imaging modalities. The advantage specifically of nanoparticles is that they can accumulate easily at the tumor site due to the large gaps in blood vessels near tumors. S...

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Detalles Bibliográficos
Autor principal: Fernandes, Donald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467409/
https://www.ncbi.nlm.nih.gov/pubmed/37642945
http://dx.doi.org/10.1177/15330338231191493
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author Fernandes, Donald A.
author_facet Fernandes, Donald A.
author_sort Fernandes, Donald A.
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description Theranostic agents are promising due to their ability to diagnose, treat and monitor different types of cancer using a variety of imaging modalities. The advantage specifically of nanoparticles is that they can accumulate easily at the tumor site due to the large gaps in blood vessels near tumors. Such high concentration of theranostic agents at the target site can lead to enhancement in both imaging and therapy. This article provides an overview of nanoparticles that have been used for cancer theranostics, and the different imaging, treatment options and signaling pathways that are important when using nanoparticles for cancer theranostics. In particular, nanoparticles made of metal elements are emphasized due to their wide applications in cancer theranostics. One important aspect discussed is the ability to combine different types of metals in one nanoplatform for use as multimodal imaging and therapeutic agents for cancer.
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spelling pubmed-104674092023-08-31 Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging Fernandes, Donald A. Technol Cancer Res Treat Image-Guided Drug Delivery in Cancer Theranostic agents are promising due to their ability to diagnose, treat and monitor different types of cancer using a variety of imaging modalities. The advantage specifically of nanoparticles is that they can accumulate easily at the tumor site due to the large gaps in blood vessels near tumors. Such high concentration of theranostic agents at the target site can lead to enhancement in both imaging and therapy. This article provides an overview of nanoparticles that have been used for cancer theranostics, and the different imaging, treatment options and signaling pathways that are important when using nanoparticles for cancer theranostics. In particular, nanoparticles made of metal elements are emphasized due to their wide applications in cancer theranostics. One important aspect discussed is the ability to combine different types of metals in one nanoplatform for use as multimodal imaging and therapeutic agents for cancer. SAGE Publications 2023-08-29 /pmc/articles/PMC10467409/ /pubmed/37642945 http://dx.doi.org/10.1177/15330338231191493 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Image-Guided Drug Delivery in Cancer
Fernandes, Donald A.
Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging
title Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging
title_full Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging
title_fullStr Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging
title_full_unstemmed Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging
title_short Review on Metal-Based Theranostic Nanoparticles for Cancer Therapy and Imaging
title_sort review on metal-based theranostic nanoparticles for cancer therapy and imaging
topic Image-Guided Drug Delivery in Cancer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467409/
https://www.ncbi.nlm.nih.gov/pubmed/37642945
http://dx.doi.org/10.1177/15330338231191493
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