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Melatonin downregulates the increased hepatic alpha-fetoprotein expression and restores pancreatic beta cells in a streptozotocin-induced diabetic rat model: a clinical, biochemical, immunohistochemical, and descriptive histopathological study
BACKGROUND: Diabetes mellitus (DM) is a chronic metabolic disorder. Hepatopathy is one of the serious effects of DM Melatonin (MT) is a potent endogenous antioxidant that can control insulin output. However, little information is available about the potential association between melatonin and hepati...
Autores principales: | Alsharif, Khalaf F., Hamad, Asmaa A., Alblihd, Mohamed A., Ali, Fatma Abo Zakaib, Mohammed, Sherine Ahmed, Theyab, Abdulrahman, Al-Amer, Osama M., Almuqati, Malik Saad, Almalki, Abdulraheem Ali, Albarakati, Alaa Jameel A., Alzahrani, Khalid J., Albrakati, Ashraf, Albarakati, Mohammad Hamed, Abass, Doaa, Lokman, Maha S., Elmahallawy, Ehab Kotb |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467430/ https://www.ncbi.nlm.nih.gov/pubmed/37655263 http://dx.doi.org/10.3389/fvets.2023.1214533 |
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