Cargando…
Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis
OBJECTIVES: This study aimed to explore real-world data on the long-term survival of cancer patients using historical records from the Surveillance, Epidemiology, and End Results (SEER) Programme. Long-term survival is an important endpoint in the management of different malignancies. It is rarely a...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467541/ https://www.ncbi.nlm.nih.gov/pubmed/37655083 http://dx.doi.org/10.18295/squmj.1.2023.002 |
_version_ | 1785099124571373568 |
---|---|
author | Sakr, Rokia A. Nasr, Abdelrahman A. Zineldin, Eman I. Gouda, Mohamed A. |
author_facet | Sakr, Rokia A. Nasr, Abdelrahman A. Zineldin, Eman I. Gouda, Mohamed A. |
author_sort | Sakr, Rokia A. |
collection | PubMed |
description | OBJECTIVES: This study aimed to explore real-world data on the long-term survival of cancer patients using historical records from the Surveillance, Epidemiology, and End Results (SEER) Programme. Long-term survival is an important endpoint in the management of different malignancies. It is rarely assessed due to the unfeasibility of follow-up for a long duration of time. Besides reporting the five-year relative survival, the 10- and 20-year survival rates for different types of cancers were analysed. Additionally, survival trends as a function of time, age and tumour type were reviewed and reported. METHODS: The study used SEER*Stat (Version 8.3.6.1) for data acquisition from the SEER 9 Regs (November 2019) database. Data from patients diagnosed with cancer between 1975 and 2014 were retrieved and included in the analysis. RESULTS: For patients diagnosed with any malignant disease (N = 4,412,024), there was a significant increase in median overall survival over time (P <0.001). The 20-, 10-, and 5-year survival rates were higher in solid tumours compared to haematological malignancies (50.8% versus 38%; 57% versus 47.4%; and 62.2% versus 57.4%, respectively). The highest 20-year relative survival rates were observed in thyroid cancer (95.2%), germ cell and trophoblastic neoplasms (90.3%), melanoma (86.8%), Wilms’ tumour (86.2%) and prostate cancer (83.5%). CONCLUSION: Long-term follow-up data were suggestive of high 20-year relative survival rates for most tumour types. Relative survival showed an improving trend over time, especially in solid tumours. |
format | Online Article Text |
id | pubmed-10467541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-104675412023-08-31 Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis Sakr, Rokia A. Nasr, Abdelrahman A. Zineldin, Eman I. Gouda, Mohamed A. Sultan Qaboos Univ Med J Clinical & Basic Research OBJECTIVES: This study aimed to explore real-world data on the long-term survival of cancer patients using historical records from the Surveillance, Epidemiology, and End Results (SEER) Programme. Long-term survival is an important endpoint in the management of different malignancies. It is rarely assessed due to the unfeasibility of follow-up for a long duration of time. Besides reporting the five-year relative survival, the 10- and 20-year survival rates for different types of cancers were analysed. Additionally, survival trends as a function of time, age and tumour type were reviewed and reported. METHODS: The study used SEER*Stat (Version 8.3.6.1) for data acquisition from the SEER 9 Regs (November 2019) database. Data from patients diagnosed with cancer between 1975 and 2014 were retrieved and included in the analysis. RESULTS: For patients diagnosed with any malignant disease (N = 4,412,024), there was a significant increase in median overall survival over time (P <0.001). The 20-, 10-, and 5-year survival rates were higher in solid tumours compared to haematological malignancies (50.8% versus 38%; 57% versus 47.4%; and 62.2% versus 57.4%, respectively). The highest 20-year relative survival rates were observed in thyroid cancer (95.2%), germ cell and trophoblastic neoplasms (90.3%), melanoma (86.8%), Wilms’ tumour (86.2%) and prostate cancer (83.5%). CONCLUSION: Long-term follow-up data were suggestive of high 20-year relative survival rates for most tumour types. Relative survival showed an improving trend over time, especially in solid tumours. Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2023-08 2023-08-28 /pmc/articles/PMC10467541/ /pubmed/37655083 http://dx.doi.org/10.18295/squmj.1.2023.002 Text en © Copyright 2023, Sultan Qaboos University Medical Journal, All Rights Reserved https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License. |
spellingShingle | Clinical & Basic Research Sakr, Rokia A. Nasr, Abdelrahman A. Zineldin, Eman I. Gouda, Mohamed A. Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis |
title | Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis |
title_full | Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis |
title_fullStr | Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis |
title_full_unstemmed | Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis |
title_short | Long-Term Survival in Patients with Cancers: Surveillance, epidemiology and end results-based analysis |
title_sort | long-term survival in patients with cancers: surveillance, epidemiology and end results-based analysis |
topic | Clinical & Basic Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467541/ https://www.ncbi.nlm.nih.gov/pubmed/37655083 http://dx.doi.org/10.18295/squmj.1.2023.002 |
work_keys_str_mv | AT sakrrokiaa longtermsurvivalinpatientswithcancerssurveillanceepidemiologyandendresultsbasedanalysis AT nasrabdelrahmana longtermsurvivalinpatientswithcancerssurveillanceepidemiologyandendresultsbasedanalysis AT zineldinemani longtermsurvivalinpatientswithcancerssurveillanceepidemiologyandendresultsbasedanalysis AT goudamohameda longtermsurvivalinpatientswithcancerssurveillanceepidemiologyandendresultsbasedanalysis |