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Click’n lock: rapid exchange between unsymmetric tetrazines and thiols for reversible, chemoselective functionalisation of biomolecules with on-demand bioorthogonal locking

The late-stage functionalisation and diversification of complex structures including biomolecules is often achieved with the help of click chemistry. Besides employing irreversible click-like reactions, many synthetic applications benefit from reversible click reaction strategies, so called de-/tran...

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Detalles Bibliográficos
Autores principales: Gavriel, Katerina, van Doeselaar, Dustin C. A., Geers, Daniëlle W. T., Neumann, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467616/
https://www.ncbi.nlm.nih.gov/pubmed/37654505
http://dx.doi.org/10.1039/d3cb00062a

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