Genome-wide causal mediation analysis identifies genetic loci associated with uterine fibroids mediated by age at menarche

STUDY QUESTION: Could the direct contribution of genetic variants to the pathophysiology of uterine fibroids and the contribution mediated by age at menarche be different? SUMMARY ANSWER: Age at menarche plays a mediation role in the genetic influence on uterine fibroids, and four causal genetic mec...

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Detalles Bibliográficos
Autores principales: Tai, An-Shun, Lin, Ro-Ting, Lin, Yi-Chun, Wang, Chung-Hsing, Lin, Sheng-Hsuan, Imoto, Seiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467635/
https://www.ncbi.nlm.nih.gov/pubmed/35689443
http://dx.doi.org/10.1093/humrep/deac136

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