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Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice

Genetic differences among mammalian hosts and among strains of Mycobacterium tuberculosis (Mtb) are well-established determinants of tuberculosis (TB) patient outcomes. The advent of recombinant inbred mouse panels and next-generation transposon mutagenesis and sequencing approaches has enabled diss...

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Detalles Bibliográficos
Autores principales:	Meade, Rachel K, Long, Jarukit E, Jinich, Adrian, Rhee, Kyu Y, Ashbrook, David G, Williams, Robert W, Sassetti, Christopher M, Smith, Clare M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Mutant Screen Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468300/ https://www.ncbi.nlm.nih.gov/pubmed/37405387 http://dx.doi.org/10.1093/g3journal/jkad147

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