An NFIX-mediated regulatory network governs the balance of hematopoietic stem and progenitor cells during hematopoiesis

The transcription factor (TF) nuclear factor I-X (NFIX) is a positive regulator of hematopoietic stem and progenitor cell (HSPC) transplantation. Nfix-deficient HSPCs exhibit a severe loss of repopulating activity, increased apoptosis, and a loss of colony-forming potential. However, the underlying...

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Detalles Bibliográficos
Autores principales: Walker, Megan, Li, Yichao, Morales-Hernandez, Antonio, Qi, Qian, Parupalli, Chaithanyarani, Brown, Scott, Christian, Claiborne, Clements, Wilson K., Cheng, Yong, McKinney-Freeman, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468369/
https://www.ncbi.nlm.nih.gov/pubmed/36478187
http://dx.doi.org/10.1182/bloodadvances.2022007811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468369/
https://www.ncbi.nlm.nih.gov/pubmed/36478187
http://dx.doi.org/10.1182/bloodadvances.2022007811

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