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Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination

Peptidylarginine deiminase (PADI) 2 catalyzes the post-translational conversion of peptidyl-arginine to peptidyl-citrulline in a process called citrullination. However, the precise functions of PADI2 in bone formation and homeostasis remain unknown. In this study, our objective was to elucidate the...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Jung, Shin, Hye-Rim, Yoon, Heein, Park, Min-Sang, Kim, Byung-Gyu, Moon, Jae-I, Kim, Woo-Jin, Park, Seung Gwa, Kim, Ki-Tae, Kim, Ha-Neui, Choi, Je-Yong, Ryoo, Hyun-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468518/
https://www.ncbi.nlm.nih.gov/pubmed/37648716
http://dx.doi.org/10.1038/s41419-023-06101-7