Polo-like kinase-1 mediates hepatitis C virus-induced cell migration, a drug target for liver cancer

Polo-like kinase 1 (PLK1) is a regulator of cell mitosis and cytoskeletal dynamics. PLK1 overexpression in liver cancer is associated with tumour progression, metastasis, and vascular invasion. Hepatitis C virus (HCV) NS5A protein stimulates PLK1-mediated phosphorylation of host proteins, so we hypo...

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Detalles Bibliográficos
Autores principales: El-Khobar, Korri E, Tay, Enoch, Diefenbach, Eve, Gloss, Brian S, George, Jacob, Douglas, Mark W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468647/
https://www.ncbi.nlm.nih.gov/pubmed/37648284
http://dx.doi.org/10.26508/lsa.202201630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468647/
https://www.ncbi.nlm.nih.gov/pubmed/37648284
http://dx.doi.org/10.26508/lsa.202201630

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