Cargando…

Effects of Melatonin on Glycemic Variability in Type 2 Diabetes Mellitus: Protocol for a Crossover, Double-Blind, Placebo-Controlled Trial

BACKGROUND: Glycemic variability is recognized as a significant factor contributing to the development of micro- and macrovascular complications in individuals with type 2 diabetes mellitus (T2DM). Numerous studies have shown that melatonin, a hormone involved in regulating various biological rhythm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martorina, Wagner, Tavares, Almir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JMIR Publications 2023
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468700/ https://www.ncbi.nlm.nih.gov/pubmed/37410852 http://dx.doi.org/10.2196/47887

Ejemplares similares

Glycemic Variability in Patients with Type 2 Diabetes Mellitus (T2DM): The Role of Melatonin in a Crossover, Double-Blind, Placebo-Controlled, Randomized Study
por: Martorina, Wagner, et al.
Publicado: (2023)

Real-World Data in Support of Short Sleep Duration with Poor Glycemic Control, in People with Type 2 Diabetes Mellitus
por: Martorina, Wagner, et al.
Publicado: (2019)

Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS)
por: Delgado, D., et al.
Publicado: (2017)

The effects of melatonin versus placebo on delirium in hip fracture patients: study protocol of a randomised, placebo-controlled, double blind trial
por: de Jonghe, Annemarieke, et al.
Publicado: (2011)

The efficacy of resveratrol in controlling hypertension: study protocol for a randomized, crossover, double-blinded, placebo-controlled trial
por: Movahed, Ali, et al.
Publicado: (2016)

Melatonin for Neuropathic Pain: Protocol for a Double-blind, Randomized Controlled Trial
por: Gilron, Ian, et al.
Publicado: (2022)

Modafinil In Debilitating fatigue After Stroke (MIDAS): study protocol for a randomised, double-blinded, placebo-controlled, crossover trial
por: Lillicrap, Thomas, et al.
Publicado: (2016)

Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial
por: van Dam, Paulien H., et al.
Publicado: (2018)

Effects of probiotics in patients with diabetes mellitus type 2: study protocol for a randomized, double-blind, placebo-controlled trial
por: Alokail, Majed S, et al.
Publicado: (2013)

Efficacy and hypnotic effects of melatonin in shift-work nurses: double-blind, placebo-controlled crossover trial
por: Sadeghniiat-Haghighi, Khosro, et al.
Publicado: (2008)

Efficacy of Ibuprofen Gargle for Postoperative Pain After Mandibular Third Molar Extraction: Protocol for a Phase II, Placebo-Controlled, Double-Blind, Randomized Crossover Trial
por: Kakei, Yasumasa, et al.
Publicado: (2022)

Moderate dose melatonin for the abatement and treatment of delirium in elderly general medical inpatients: study protocol of a placebo controlled, randomised, double blind trial
por: Clayton-Chubb, Daniel I., et al.
Publicado: (2016)

Probiotics for glycemic control in patients with type 2 diabetes mellitus: protocol for a systematic review
por: Rittiphairoj, Thanitsara, et al.
Publicado: (2019)

An Investigation of Levetiracetam in Alzheimer’s Disease (ILiAD): a double-blind, placebo-controlled, randomised crossover proof of concept study
por: Sen, Arjune, et al.
Publicado: (2021)

Efficacy and safety of exogenous ketone bodies for preventive treatment of migraine: A study protocol for a single-centred, randomised, placebo-controlled, double-blind crossover trial
por: Gross, Elena, et al.
Publicado: (2019)

Jakyakgamcho-tang in the relief of delayed-onset muscle soreness in healthy adults: study protocol for a randomized, double-blind, placebo-controlled, crossover design clinical trial
por: Han, Kyungsun, et al.
Publicado: (2020)

Innovations in the Management of Musculoskeletal Pain With Alpha-Lipoic Acid (IMPALA Trial): Study protocol for a Double-Blind, Randomized, Placebo-Controlled Crossover Trial of Alpha-Lipoic Acid for the Treatment of Fibromyalgia Pain
por: Gilron, Ian, et al.
Publicado: (2017)

Effect of dietary prebiotic supplementation on advanced glycation, insulin resistance and inflammatory biomarkers in adults with pre-diabetes: a study protocol for a double-blind placebo-controlled randomised crossover clinical trial
por: Kellow, Nicole J, et al.
Publicado: (2014)

Orange Pomace Improves Postprandial Glycemic Responses: An Acute, Randomized, Placebo-Controlled, Double-Blind, Crossover Trial in Overweight Men
por: Chen, C.-Y. Oliver, et al.
Publicado: (2017)

Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial
por: Selvarajah, Dinesh, et al.
Publicado: (2018)

PAciFy Cough—a multicentre, double-blind, placebo-controlled, crossover trial of morphine sulphate for the treatment of pulmonary Fibrosis Cough
por: Wu, Zhe, et al.
Publicado: (2022)

N-acetyl-L-leucine for Niemann-Pick type C: a multinational double-blind randomized placebo-controlled crossover study
por: Fields, T, et al.
Publicado: (2023)

Combination Analgesic Development for Enhanced Clinical Efficacy (CADENCE Trial): Study Protocol for a Double-Blind, Randomized, Placebo-Controlled Crossover Trial of an Alpha-Lipoic Acid – Pregabalin Combination for the Treatment of Fibromyalgia Pain
por: Gilron, Ian, et al.
Publicado: (2017)

Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial
por: Feil, Katharina, et al.
Publicado: (2017)

Efficacy of different spinal cord stimulation paradigms for the treatment of chronic neuropathic pain (PARS-trial): study protocol for a double-blinded, randomized, and placebo-controlled crossover trial
por: Ahmadi, Rezvan, et al.
Publicado: (2021)

Effect of Dapagliflozin as an Add-on Therapy to Insulin on the Glycemic Variability in Subjects with Type 2 Diabetes Mellitus (DIVE): A Multicenter, Placebo-Controlled, Double-Blind, Randomized Study
por: Lee, Seung-Hwan, et al.
Publicado: (2021)

A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a randomized controlled trial
por: Barlow, Karen M, et al.
Publicado: (2014)

A six-month prospective, randomised, double-blinded, placebo-controlled, crossover, dietary trial design to investigate the potential of psychobiotics on seizure semiology and comorbidities in canine epilepsy: study protocol
por: Schmidt, Teresa, et al.
Publicado: (2023)

Significance of Glycemic Variability in Diabetes Mellitus
por: Kusunoki, Yoshiki, et al.
Publicado: (2021)

A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation
por: Haidinger, Michael, et al.
Publicado: (2010)

Treatment with Creatine Monohydrate in Spinal and Bulbar Muscular Atrophy: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial
por: Hijikata, Yasuhiro, et al.
Publicado: (2018)

Statin treatment for unruptured intracranial aneurysms study: a study protocol for a double-blind, placebo-controlled trial
por: Li, Wenqiang, et al.
Publicado: (2020)

Randomised, double-blind, placebo-controlled trial of glycopyrronium in children and adolescents with severe sialorrhoea and neurodisabilities: protocol of the SALIVA trial
por: Fayoux, Pierre, et al.
Publicado: (2023)

Efficacy and safety of prolonged-release melatonin in insomnia patients with diabetes: a randomized, double-blind, crossover study
por: Garfinkel, Doron, et al.
Publicado: (2011)

Effects of supplemental oxygen on systemic and cerebral hemodynamics in experimental hypovolemia: Protocol for a randomized, double blinded crossover study
por: Lindvåg Lie, Sole, et al.
Publicado: (2022)

Design and rationale for the randomised, double-blinded, placebo-controlled Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS) crossover study
por: Myat, Aung, et al.
Publicado: (2015)

Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS)
por: Drake, Marcus J., et al.
Publicado: (2018)

Denosumab for treating periprosthetic osteolysis; study protocol for a randomized, double-blind, placebo-controlled trial
por: Sköldenberg, Olof, et al.
Publicado: (2016)

Efficacy and safety of berberine for dyslipidemia: study protocol for a randomized double-blind placebo-controlled trial
por: Zhao, Ying, et al.
Publicado: (2021)

Low-dose naltrexone for the treatment of fibromyalgia: protocol for a double-blind, randomized, placebo-controlled trial
por: Bruun, Karin Due, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_baadf07da6gou50n6n8tebo503