Hepatocyte-specific Sox9 knockout ameliorates acute liver injury by suppressing SHP signaling and improving mitochondrial function

BACKGROUND AND AIMS: Sex determining region Y related high-mobility group box protein 9 (Sox9) is expressed in a subset of hepatocytes, and it is important for chronic liver injury. However, the roles of Sox9(+) hepatocytes in response to the acute liver injury and repair are poorly understood. METH...

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Detalles Bibliográficos
Autores principales: Qin, Dan, Wang, Rui, Ji, Jinwei, Wang, Duo, Lu, Yuanyuan, Cao, Shiyao, Chen, Yaqing, Wang, Liqiang, Chen, Xiangmei, Zhang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468867/
https://www.ncbi.nlm.nih.gov/pubmed/37649095
http://dx.doi.org/10.1186/s13578-023-01104-5

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