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The high level of IL-1β in the serum of ACLF patients induces increased IL-8 expression in hUC-MSCs and reduces the efficacy of hUC-MSCs in liver failure

BACKGROUND: Stem cells play a therapeutic role mainly through immunoregulation. However, the immunomodulatory function of stem cells may be affected by inflammation-related factors in patients’ serum. Therefore, this study aims to investigate the possible mechanism by which acute-on-chronic liver fa...

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Detalles Bibliográficos
Autores principales: Wang, Yong-Hong, Wang, Meng-Lan, Tao, Ya-Chao, Wu, Dong-Bo, Chen, En-Qiang, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468895/
https://www.ncbi.nlm.nih.gov/pubmed/37649110
http://dx.doi.org/10.1186/s13287-023-03455-9