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The high level of IL-1β in the serum of ACLF patients induces increased IL-8 expression in hUC-MSCs and reduces the efficacy of hUC-MSCs in liver failure
BACKGROUND: Stem cells play a therapeutic role mainly through immunoregulation. However, the immunomodulatory function of stem cells may be affected by inflammation-related factors in patients’ serum. Therefore, this study aims to investigate the possible mechanism by which acute-on-chronic liver fa...
Autores principales: | Wang, Yong-Hong, Wang, Meng-Lan, Tao, Ya-Chao, Wu, Dong-Bo, Chen, En-Qiang, Tang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468895/ https://www.ncbi.nlm.nih.gov/pubmed/37649110 http://dx.doi.org/10.1186/s13287-023-03455-9 |
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