Potential Anti-Mpox Virus Activity of Atovaquone, Mefloquine, and Molnupiravir, and Their Potential Use as Treatments

BACKGROUND: Mpox virus (MPXV) is a zoonotic orthopoxvirus and caused an outbreak in 2022. Although tecovirimat and brincidofovir are approved as anti-smallpox drugs, their effects in mpox patients have not been well documented. In this study, by a drug repurposing approach, we identified potential d...

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Detalles Bibliográficos
Autores principales: Akazawa, Daisuke, Ohashi, Hirofumi, Hishiki, Takayuki, Morita, Takeshi, Iwanami, Shoya, Kim, Kwang Su, Jeong, Yong Dam, Park, Eun-Sil, Kataoka, Michiyo, Shionoya, Kaho, Mifune, Junki, Tsuchimoto, Kana, Ojima, Shinjiro, Azam, Aa Haeruman, Nakajima, Shogo, Park, Hyeongki, Yoshikawa, Tomoki, Shimojima, Masayuki, Kiga, Kotaro, Iwami, Shingo, Maeda, Ken, Suzuki, Tadaki, Ebihara, Hideki, Takahashi, Yoshimasa, Watashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469127/
https://www.ncbi.nlm.nih.gov/pubmed/36892247
http://dx.doi.org/10.1093/infdis/jiad058

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