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Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study
Objectives: To characterize bedside 24-h patterns in light exposure in the Neonatal Intensive Care Unit (NICU) and to explore the environmental and individual patient characteristics that influence these patterns in this clinical setting. Methods: We conducted a retrospective cohort study that inclu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469299/ https://www.ncbi.nlm.nih.gov/pubmed/37664437 http://dx.doi.org/10.3389/fphys.2023.1217660 |
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author | Van der Linden, Isabelle A. Hazelhoff, Esther M. De Groot, Eline R. Vijlbrief, Daniel C. Schlangen, Luc J. M. De Kort, Yvonne A. W. Vermeulen, Marijn J. Van Gilst, Demy Dudink, Jeroen Kervezee, Laura |
author_facet | Van der Linden, Isabelle A. Hazelhoff, Esther M. De Groot, Eline R. Vijlbrief, Daniel C. Schlangen, Luc J. M. De Kort, Yvonne A. W. Vermeulen, Marijn J. Van Gilst, Demy Dudink, Jeroen Kervezee, Laura |
author_sort | Van der Linden, Isabelle A. |
collection | PubMed |
description | Objectives: To characterize bedside 24-h patterns in light exposure in the Neonatal Intensive Care Unit (NICU) and to explore the environmental and individual patient characteristics that influence these patterns in this clinical setting. Methods: We conducted a retrospective cohort study that included 79 very preterm infants who stayed in an incubator with a built-in light sensor. Bedside light exposure was measured continuously (one value per minute). Based on these data, various metrics (including relative amplitude, intradaily variability, and interdaily stability) were calculated to characterize the 24-h patterns of light exposure. Next, we determined the association between these metrics and various environmental and individual patient characteristics. Results: A 24-h light-dark cycle was apparent in the NICU with significant differences in light exposure between the three nurse shifts (p < 0.001), with the highest values in the morning and the lowest values at night. Light exposure was generally low, with illuminances rarely surpassing 75 lux, and highly variable between patients and across days within a single patient. Furthermore, the season of birth and phototherapy had a significant effect on 24-h light-dark cycles, whereas no effect of bed location and illness severity were observed. Conclusion: Even without an official lighting regime set, a 24-h light-dark cycle was observed in the NICU. Various rhythmicity metrics can be used to characterize 24-h light-dark cycles in a clinical setting and to study the relationship between light patterns and health outcomes. |
format | Online Article Text |
id | pubmed-10469299 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104692992023-09-01 Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study Van der Linden, Isabelle A. Hazelhoff, Esther M. De Groot, Eline R. Vijlbrief, Daniel C. Schlangen, Luc J. M. De Kort, Yvonne A. W. Vermeulen, Marijn J. Van Gilst, Demy Dudink, Jeroen Kervezee, Laura Front Physiol Physiology Objectives: To characterize bedside 24-h patterns in light exposure in the Neonatal Intensive Care Unit (NICU) and to explore the environmental and individual patient characteristics that influence these patterns in this clinical setting. Methods: We conducted a retrospective cohort study that included 79 very preterm infants who stayed in an incubator with a built-in light sensor. Bedside light exposure was measured continuously (one value per minute). Based on these data, various metrics (including relative amplitude, intradaily variability, and interdaily stability) were calculated to characterize the 24-h patterns of light exposure. Next, we determined the association between these metrics and various environmental and individual patient characteristics. Results: A 24-h light-dark cycle was apparent in the NICU with significant differences in light exposure between the three nurse shifts (p < 0.001), with the highest values in the morning and the lowest values at night. Light exposure was generally low, with illuminances rarely surpassing 75 lux, and highly variable between patients and across days within a single patient. Furthermore, the season of birth and phototherapy had a significant effect on 24-h light-dark cycles, whereas no effect of bed location and illness severity were observed. Conclusion: Even without an official lighting regime set, a 24-h light-dark cycle was observed in the NICU. Various rhythmicity metrics can be used to characterize 24-h light-dark cycles in a clinical setting and to study the relationship between light patterns and health outcomes. Frontiers Media S.A. 2023-08-16 /pmc/articles/PMC10469299/ /pubmed/37664437 http://dx.doi.org/10.3389/fphys.2023.1217660 Text en Copyright © 2023 Van der Linden, Hazelhoff, De Groot, Vijlbrief, Schlangen, De Kort, Vermeulen, Van Gilst, Dudink and Kervezee. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Van der Linden, Isabelle A. Hazelhoff, Esther M. De Groot, Eline R. Vijlbrief, Daniel C. Schlangen, Luc J. M. De Kort, Yvonne A. W. Vermeulen, Marijn J. Van Gilst, Demy Dudink, Jeroen Kervezee, Laura Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study |
title | Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study |
title_full | Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study |
title_fullStr | Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study |
title_full_unstemmed | Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study |
title_short | Characterizing light-dark cycles in the Neonatal Intensive Care Unit: a retrospective observational study |
title_sort | characterizing light-dark cycles in the neonatal intensive care unit: a retrospective observational study |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469299/ https://www.ncbi.nlm.nih.gov/pubmed/37664437 http://dx.doi.org/10.3389/fphys.2023.1217660 |
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