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Nucleus accumbens shell neurons’ early sensitivity to cocaine is associated with future increases in drug intake

The striatum, both dorsal and ventral, is strongly implicated in substance use disorder. Chronic consumption of abused substances, such as cocaine, can cause an oversaturation of mesostriatal dopamine, which results in alterations in the firing of striatal neurons. While most preclinical studies of...

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Detalles Bibliográficos
Autores principales: Crawley, Ashley K., Sharma, Anirudh, Coffey, Kevin R., West, Mark O., Barker, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469398/
https://www.ncbi.nlm.nih.gov/pubmed/37664219
http://dx.doi.org/10.1016/j.addicn.2023.100107