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The HLA class I immunopeptidomes of AAV capsid proteins

INTRODUCTION: Cellular immune responses against AAV vector capsid represent an obstacle for successful gene therapy. Previous studies have used overlapping peptides spanning the entire capsid sequence to identify T cell epitopes recognized by AAV-specific CD8+ T cells. However, the repertoire of pep...

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Detalles Bibliográficos
Autores principales:	Brito-Sierra, Carlos A., Lannan, Megan B., Malherbe, Laurent P., Siegel, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469481/ https://www.ncbi.nlm.nih.gov/pubmed/37662941 http://dx.doi.org/10.3389/fimmu.2023.1212136

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