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Assessment of HLA-DPB1 genetic variation using an HLA-DP tool and its implications in clinical transplantation

HLA-DP is a classic transplantation antigen that mediates alloreactivity through T-cell epitope (TCE) diversity and expression levels. A current challenge is to integrate these functional features into the prospective selection of unrelated donor candidates for transplantation. Genetically, HLA-DPB1...

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Detalles Bibliográficos
Autores principales: Sajulga, Ray, Bolon, Yung-Tsi, Maiers, Martin J., Petersdorf, Effie W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469530/
https://www.ncbi.nlm.nih.gov/pubmed/37126658
http://dx.doi.org/10.1182/bloodadvances.2022009554