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Proinflammatory state promotes red blood cell alloimmunization in pediatric patients with sickle cell disease

We examined risk factors for red blood cell (RBC) alloimmunization in pediatric patients with sickle cell disease, focusing on the recipients’ inflammatory state at the time of transfusion and anti-inflammatory role of hydroxyurea (HU). Among 471 participants, 55 (11.70%) participants were alloimmun...

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Detalles Bibliográficos
Autores principales:	Zheng, Yan, Gossett, Jeffrey M., Chen, Pei-Lin, Barton, Martha, Ryan, Missy, Yu, Jing, Kang, Guolian, Hankins, Jane S., Chou, Stella T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2023
Materias:	Transfusion Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469551/ https://www.ncbi.nlm.nih.gov/pubmed/37023228 http://dx.doi.org/10.1182/bloodadvances.2022008647

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