Genome-wide meta-analysis identifies new candidate genes for sickle cell disease nephropathy

Sickle cell disease nephropathy (SCDN), a common SCD complication, is strongly associated with mortality. Polygenic risk scores calculated from recent transethnic meta-analyses of urinary albumin-to-creatinine ratio and estimated glomerular filtration rate (eGFR) trended toward association with prot...

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Detalles Bibliográficos
Autores principales: Garrett, Melanie E., Soldano, Karen L., Erwin, Kyle N., Zhang, Yingze, Gordeuk, Victor R., Gladwin, Mark T., Telen, Marilyn J., Ashley-Koch, Allison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469559/
https://www.ncbi.nlm.nih.gov/pubmed/36399516
http://dx.doi.org/10.1182/bloodadvances.2022007451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469559/
https://www.ncbi.nlm.nih.gov/pubmed/36399516
http://dx.doi.org/10.1182/bloodadvances.2022007451

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