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Genome-wide meta-analysis identifies new candidate genes for sickle cell disease nephropathy
Sickle cell disease nephropathy (SCDN), a common SCD complication, is strongly associated with mortality. Polygenic risk scores calculated from recent transethnic meta-analyses of urinary albumin-to-creatinine ratio and estimated glomerular filtration rate (eGFR) trended toward association with prot...
Autores principales: | Garrett, Melanie E., Soldano, Karen L., Erwin, Kyle N., Zhang, Yingze, Gordeuk, Victor R., Gladwin, Mark T., Telen, Marilyn J., Ashley-Koch, Allison E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469559/ https://www.ncbi.nlm.nih.gov/pubmed/36399516 http://dx.doi.org/10.1182/bloodadvances.2022007451 |
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