Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity

The chemokine CCL21 regulates immune and cancer cell migration through its receptor CCR7. The Ccl21a gene encodes the isoform CCL21-Ser, predominantly expressed in the thymic medulla and the secondary lymphoid tissues. This study examined the roles of CCL21-Ser in the antitumor immune response in Cc...

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Detalles Bibliográficos
Autores principales: Fujie, Ryonosuke, Kurowarabe, Kaoru, Yamada, Yuki, Fujiwara, Kakeru, Nakatani, Hayato, Tsutsumi, Kenta, Hayashi, Ryota, Kawahata, Hinami, Miyamoto, Megumi, Ozawa, Madoka, Katakai, Tomoya, Takahama, Yousuke, Ohigashi, Izumi, Hayasaka, Haruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469598/
https://www.ncbi.nlm.nih.gov/pubmed/37664721
http://dx.doi.org/10.1016/j.heliyon.2023.e19215

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