Mutation in the two-component regulator BaeSR mediates cefiderocol resistance and enhances virulence in Acinetobacter baumannii

Acinetobacter baumannii has become one of the most challenging pathogens in many countries with limited treatment options available. Cefiderocol, a novel siderophore-conjugated cephalosporin, shows potent in vitro activity against A. baumannii, including isolates resistant to carbapenems. To date, f...

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Detalles Bibliográficos
Autores principales: Liu, Xiaochen, Chang, Yunjie, Xu, Qingye, Zhang, Wang, Huang, Zhen, Zhang, Linyue, Weng, Shanshan, Leptihn, Sebastian, Jiang, Yan, Yu, Yunsong, Hua, Xiaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469669/
https://www.ncbi.nlm.nih.gov/pubmed/37345941
http://dx.doi.org/10.1128/msystems.01291-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469669/
https://www.ncbi.nlm.nih.gov/pubmed/37345941
http://dx.doi.org/10.1128/msystems.01291-22

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