Intratumor microbiome derived glycolysis-lactate signatures depicts immune heterogeneity in lung adenocarcinoma by integration of microbiomic, transcriptomic, proteomic and single-cell data

INTRODUCTION: Microbiome plays roles in lung adenocarcinoma (LUAD) development and anti-tumor treatment efficacy. Aberrant glycolysis in tumor might promote lactate production that alter tumor microenvironment, affecting microbiome, cancer cells and immune cells. We aimed to construct intratumor mic...

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Detalles Bibliográficos
Autores principales: Deng, Xiaheng, Chen, Xiru, Luo, Yu, Que, Jun, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469687/
https://www.ncbi.nlm.nih.gov/pubmed/37664112
http://dx.doi.org/10.3389/fmicb.2023.1202454

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