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Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy

Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are immune-mediated chronic inflammatory diseases that target the gastrointestinal tract and other distant organs. The incidence of IBDs has been rising and is more prevailing in Western communities. The etiol...

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Autores principales: Mahmoud, Anas, Begg, Maha, Tarhuni, Mawada, N. Fotso, Monique, Gonzalez, Natalie A, Sanivarapu, Raghavendra R, Osman, Usama, Latha Kumar, Abishek, Sadagopan, Aishwarya, Alfonso, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469711/
https://www.ncbi.nlm.nih.gov/pubmed/37664383
http://dx.doi.org/10.7759/cureus.42786
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author Mahmoud, Anas
Begg, Maha
Tarhuni, Mawada
N. Fotso, Monique
Gonzalez, Natalie A
Sanivarapu, Raghavendra R
Osman, Usama
Latha Kumar, Abishek
Sadagopan, Aishwarya
Alfonso, Michael
author_facet Mahmoud, Anas
Begg, Maha
Tarhuni, Mawada
N. Fotso, Monique
Gonzalez, Natalie A
Sanivarapu, Raghavendra R
Osman, Usama
Latha Kumar, Abishek
Sadagopan, Aishwarya
Alfonso, Michael
author_sort Mahmoud, Anas
collection PubMed
description Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are immune-mediated chronic inflammatory diseases that target the gastrointestinal tract and other distant organs. The incidence of IBDs has been rising and is more prevailing in Western communities. The etiology has been vague, but different theories include environmental factors that elicit an uncontrolled immune response, which damages internal organs. Treatment of either Crohn's disease or ulcerative colitis has witnessed significant advances; however, pharmacological drugs' side effects limit their use. Research about microbiota and its influence on IBDs has gained fame, and multiple studies correlate microbiota diversity positively with IBD treatment. Many factors contribute to the microbiota's health, including different diets, antibiotics, prebiotics, probiotics, synbiotics, and postbiotics. Specific immune responses lie behind the pathogenesis of IBDs and microbiota dysbiosis, and different studies have postulated new ways to control this abnormal response. Physical activity, sun exposure, efficient sleep, intermittent fasting, and supplementation of probiotics and vitamins are natural ways that help modulate this immune response, do not cost money as IBD pharmacological drugs, and do not come with deleterious side effects that are sometimes more harmful than IBDs. Our article proposes a comprehensive natural approach that can benefit IBD patients enormously. This approach does not replace the medications currently used in treating IBDs. The suggested approach can be used in combination with medications and might aid in reducing the doses of those medications.
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spelling pubmed-104697112023-09-01 Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy Mahmoud, Anas Begg, Maha Tarhuni, Mawada N. Fotso, Monique Gonzalez, Natalie A Sanivarapu, Raghavendra R Osman, Usama Latha Kumar, Abishek Sadagopan, Aishwarya Alfonso, Michael Cureus Allergy/Immunology Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are immune-mediated chronic inflammatory diseases that target the gastrointestinal tract and other distant organs. The incidence of IBDs has been rising and is more prevailing in Western communities. The etiology has been vague, but different theories include environmental factors that elicit an uncontrolled immune response, which damages internal organs. Treatment of either Crohn's disease or ulcerative colitis has witnessed significant advances; however, pharmacological drugs' side effects limit their use. Research about microbiota and its influence on IBDs has gained fame, and multiple studies correlate microbiota diversity positively with IBD treatment. Many factors contribute to the microbiota's health, including different diets, antibiotics, prebiotics, probiotics, synbiotics, and postbiotics. Specific immune responses lie behind the pathogenesis of IBDs and microbiota dysbiosis, and different studies have postulated new ways to control this abnormal response. Physical activity, sun exposure, efficient sleep, intermittent fasting, and supplementation of probiotics and vitamins are natural ways that help modulate this immune response, do not cost money as IBD pharmacological drugs, and do not come with deleterious side effects that are sometimes more harmful than IBDs. Our article proposes a comprehensive natural approach that can benefit IBD patients enormously. This approach does not replace the medications currently used in treating IBDs. The suggested approach can be used in combination with medications and might aid in reducing the doses of those medications. Cureus 2023-08-01 /pmc/articles/PMC10469711/ /pubmed/37664383 http://dx.doi.org/10.7759/cureus.42786 Text en Copyright © 2023, Mahmoud et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Mahmoud, Anas
Begg, Maha
Tarhuni, Mawada
N. Fotso, Monique
Gonzalez, Natalie A
Sanivarapu, Raghavendra R
Osman, Usama
Latha Kumar, Abishek
Sadagopan, Aishwarya
Alfonso, Michael
Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy
title Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy
title_full Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy
title_fullStr Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy
title_full_unstemmed Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy
title_short Inflammatory Bowel Sugar Disease: A Pause From New Pharmacological Agents and an Embrace of Natural Therapy
title_sort inflammatory bowel sugar disease: a pause from new pharmacological agents and an embrace of natural therapy
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469711/
https://www.ncbi.nlm.nih.gov/pubmed/37664383
http://dx.doi.org/10.7759/cureus.42786
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