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DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus

Palmitoyl acyltransferases (PATs) have been suggested to be involved in learning and memory. However, the underlying mechanisms have not yet been fully elucidated. Here, we found that the activity of DHHC2 was upregulated in the hippocampus after fear conditioning, and DHHC2 knockdown impaired fear...

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Detalles Bibliográficos
Autores principales: Li, Meng-Die, Wang, Lu, Zheng, Yu-Qi, Huang, Dan-Hong, Xia, Zhi-Xuan, Liu, Jian-Min, Tian, Dan, OuYang, Hui, Wang, Zi-Hao, Huang, Zhen, Lin, Xiao-Shan, Zhu, Xiao-Qian, Wang, Si-Ying, Chen, Wei-Kai, Yang, Shao-Wei, Zhao, Yue-Ling, Liu, Jia-An, Shen, Zu-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469764/
https://www.ncbi.nlm.nih.gov/pubmed/37664599
http://dx.doi.org/10.1016/j.isci.2023.107561