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Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition

Short-chain fatty acids (SCFAs, especially butyric acid) have been demonstrated to play a promising role in the development of autism spectrum disorders (ASD). Recently, the hypothalamic–pituitary–adrenal (HPA) axis is also suggested to increase the risk of ASD. However, the mechanism underlying SCF...

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Detalles Bibliográficos
Autores principales: Wang, Xinyuan, Sun, Zhujun, Yang, Ting, Lin, Fang, Ye, Shasha, Yan, Junyan, Li, Tingyu, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469781/
https://www.ncbi.nlm.nih.gov/pubmed/37358267
http://dx.doi.org/10.1128/msystems.00415-23