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Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition
Short-chain fatty acids (SCFAs, especially butyric acid) have been demonstrated to play a promising role in the development of autism spectrum disorders (ASD). Recently, the hypothalamic–pituitary–adrenal (HPA) axis is also suggested to increase the risk of ASD. However, the mechanism underlying SCF...
Autores principales: | Wang, Xinyuan, Sun, Zhujun, Yang, Ting, Lin, Fang, Ye, Shasha, Yan, Junyan, Li, Tingyu, Chen, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469781/ https://www.ncbi.nlm.nih.gov/pubmed/37358267 http://dx.doi.org/10.1128/msystems.00415-23 |
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