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Research progress on the anti-tumor effect of Naringin

Naringin is a kind of natural dihydro flavone, which mainly exists in citrus fruits of the Rutaceae family, as well as traditional Chinese medicines such as trifoliate orange, fingered citron, exocarpium citri grandis, and rhizoma dynamite. Modern pharmacological studies have shown that Naringin has...

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Autores principales: He, Jing, Zhang, Hui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469811/
https://www.ncbi.nlm.nih.gov/pubmed/37663256
http://dx.doi.org/10.3389/fphar.2023.1217001
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author He, Jing
Zhang, Hui-Ping
author_facet He, Jing
Zhang, Hui-Ping
author_sort He, Jing
collection PubMed
description Naringin is a kind of natural dihydro flavone, which mainly exists in citrus fruits of the Rutaceae family, as well as traditional Chinese medicines such as trifoliate orange, fingered citron, exocarpium citri grandis, and rhizoma dynamite. Modern pharmacological studies have shown that Naringin has excellent anti-tumor activity. Through reviewing the relevant literature at home and abroad in recent years, we summarized the pharmacological mechanism of Naringin to play an anti-cancer role in blocking tumor cell cycle, inhibiting tumor cell proliferation, inducing tumor cell apoptosis, inhibiting tumor cell invasion and metastasis, inducing tumor cell autophagy, reversing tumor cell drug resistance and enhancing chemotherapeutic drug sensitivity, as well as anti-inflammatory to prevent canceration, alleviate Adverse drug reaction of chemotherapy, activate and strengthen immunity, It provides theoretical basis and reference basis for further exploring the anticancer potential of Naringin and its further development and utilization.
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spelling pubmed-104698112023-09-01 Research progress on the anti-tumor effect of Naringin He, Jing Zhang, Hui-Ping Front Pharmacol Pharmacology Naringin is a kind of natural dihydro flavone, which mainly exists in citrus fruits of the Rutaceae family, as well as traditional Chinese medicines such as trifoliate orange, fingered citron, exocarpium citri grandis, and rhizoma dynamite. Modern pharmacological studies have shown that Naringin has excellent anti-tumor activity. Through reviewing the relevant literature at home and abroad in recent years, we summarized the pharmacological mechanism of Naringin to play an anti-cancer role in blocking tumor cell cycle, inhibiting tumor cell proliferation, inducing tumor cell apoptosis, inhibiting tumor cell invasion and metastasis, inducing tumor cell autophagy, reversing tumor cell drug resistance and enhancing chemotherapeutic drug sensitivity, as well as anti-inflammatory to prevent canceration, alleviate Adverse drug reaction of chemotherapy, activate and strengthen immunity, It provides theoretical basis and reference basis for further exploring the anticancer potential of Naringin and its further development and utilization. Frontiers Media S.A. 2023-08-17 /pmc/articles/PMC10469811/ /pubmed/37663256 http://dx.doi.org/10.3389/fphar.2023.1217001 Text en Copyright © 2023 He and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
He, Jing
Zhang, Hui-Ping
Research progress on the anti-tumor effect of Naringin
title Research progress on the anti-tumor effect of Naringin
title_full Research progress on the anti-tumor effect of Naringin
title_fullStr Research progress on the anti-tumor effect of Naringin
title_full_unstemmed Research progress on the anti-tumor effect of Naringin
title_short Research progress on the anti-tumor effect of Naringin
title_sort research progress on the anti-tumor effect of naringin
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469811/
https://www.ncbi.nlm.nih.gov/pubmed/37663256
http://dx.doi.org/10.3389/fphar.2023.1217001
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