Cargando…

Therapeutic potential of TNFR2 agonists: a mechanistic perspective

TNFR2 agonists have been investigated as potential therapies for inflammatory diseases due to their ability to activate and expand immunosuppressive CD4+Foxp3+ Treg cells and myeloid-derived suppressor cells (MDSCs). Despite TNFR2 being predominantly expressed in Treg cells at high levels, activated...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yibo, Jiang, Mengmeng, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469862/
https://www.ncbi.nlm.nih.gov/pubmed/37662935
http://dx.doi.org/10.3389/fimmu.2023.1209188