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Therapeutic potential of TNFR2 agonists: a mechanistic perspective
TNFR2 agonists have been investigated as potential therapies for inflammatory diseases due to their ability to activate and expand immunosuppressive CD4+Foxp3+ Treg cells and myeloid-derived suppressor cells (MDSCs). Despite TNFR2 being predominantly expressed in Treg cells at high levels, activated...
Autores principales: | Chen, Yibo, Jiang, Mengmeng, Chen, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469862/ https://www.ncbi.nlm.nih.gov/pubmed/37662935 http://dx.doi.org/10.3389/fimmu.2023.1209188 |
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