Cargando…

Delineating intra-tumoral heterogeneity and tumor evolution in breast cancer using precision-based approaches

The burden of breast cancer continues to increase worldwide as it remains the most diagnosed tumor in females and the second leading cause of cancer-related deaths. Breast cancer is a heterogeneous disease characterized by different subtypes which are driven by aberrations in key genes such as BRCA1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xulu, Kutlwano Rekgopetswe, Nweke, Ekene Emmanuel, Augustine, Tanya Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469897/ https://www.ncbi.nlm.nih.gov/pubmed/37662839 http://dx.doi.org/10.3389/fgene.2023.1087432

Ejemplares similares

HAART induces cell death in a cervical cancer cell line, HCS-2: A Scanning Electron Microscopy study
por: Xulu, Kutlwano Rekgopetswe, et al.
Publicado: (2017)

Antiplatelet Therapy Combined with Anastrozole Induces Features of Partial EMT in Breast Cancer Cells and Fails to Mitigate Breast-Cancer Induced Hypercoagulation
por: Xulu, Kutlwano R., et al.
Publicado: (2021)

Targeting Platelet Activation Pathways to Limit Tumour Progression: Current State of Affairs
por: Xulu, Kutlwano R., et al.
Publicado: (2022)

Exploiting the molecular subtypes and genetic landscape in pancreatic cancer: the quest to find effective drugs
por: Elebo, Nnenna, et al.
Publicado: (2023)

Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
por: Baichan, Pavan, et al.
Publicado: (2023)

Breast cancer intra-tumor heterogeneity
por: Martelotto, Luciano G, et al.
Publicado: (2014)

Editorial: Multi-omics analysis in tumor microenvironment and tumor heterogeneity
por: Shi, Yuxin, et al.
Publicado: (2023)

Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications
por: Cresswell, George D., et al.
Publicado: (2016)

Spatial Transcriptomics for Tumor Heterogeneity Analysis
por: Li, Qiongyu, et al.
Publicado: (2022)

DNA methylation profiles delineate epigenetic heterogeneity in seminoma and non-seminoma
por: Brait, M, et al.
Publicado: (2012)

Intra-Familial Phenotypic Heterogeneity and Telomere Abnormality in von Hippel- Lindau Disease: Implications for Personalized Surveillance Plan and Pathogenesis of VHL-Associated Tumors
por: Wang, Jiangyi, et al.
Publicado: (2019)

Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications
por: de Bruin, Elza C, et al.
Publicado: (2013)

Unmasking Intra-Tumoral Heterogeneity and Clonal Evolution in NF1-MPNST
por: Moon, Chang-In, et al.
Publicado: (2020)

Downregulation of the let-7 family of microRNAs may promote insulin receptor/insulin-like growth factor signalling pathways in pancreatic ductal adenocarcinoma
por: Nweke, Ekene Emmanuel, et al.
Publicado: (2020)

Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine
por: Parasido, Erika Maria, et al.
Publicado: (2016)

Phylogenetic Tree Inference: A Top-Down Approach to Track Tumor Evolution
por: Wu, Pin, et al.
Publicado: (2020)

Collaborative intra-tumor heterogeneity detection
por: Khakabimamaghani, Sahand, et al.
Publicado: (2019)

Phenotypic Heterogeneity in Tumor Progression, and Its Possible Role in the Onset of Cancer
por: Deshmukh, Saniya, et al.
Publicado: (2020)

Genetic Heterogeneity and Clonal Evolution of Tumor Cells and their Impact on Precision Cancer Medicine
por: Sabaawy, Hatem E
Publicado: (2013)

Genomic and Transcriptomic Landscape of Tumor Clonal Evolution in Cholangiocarcinoma
por: Chen, Geng, et al.
Publicado: (2020)

Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma
por: Affinito, Ornella, et al.
Publicado: (2022)

Genetic and microenvironmental intra-tumor heterogeneity impacts colorectal cancer evolution and metastatic development
por: Sobral, Daniel, et al.
Publicado: (2022)

Intra-tumor Genetic Heterogeneity in Rectal Cancer
por: Hardiman, Karin M., et al.
Publicado: (2015)

Overview on Clinical Relevance of Intra-Tumor Heterogeneity
por: Stanta, Giorgio, et al.
Publicado: (2018)

Addressing intra-tumoral heterogeneity and therapy resistance
por: Rybinski, Brad, et al.
Publicado: (2016)

Chemokine receptor 8 expression may be linked to disease severity and elevated interleukin 6 secretion in acute pancreatitis
por: Nalisa, Mwangala, et al.
Publicado: (2021)

Methodological Advancements for Investigating Intra-tumoral Heterogeneity in Breast Cancer at the Bench and Bedside
por: Baek, Mokryun, et al.
Publicado: (2020)

Role of 5-methylcytosine in determining the prognosis, tumor microenvironment, and applicability of precision medicine in patients with hepatocellular carcinoma
por: Luan, Mingyuan, et al.
Publicado: (2022)

Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer
por: Cooke, S L, et al.
Publicado: (2011)

Gene expression-based dissection of inter-histotypes, intra-histotype and intra-tumor heterogeneity in pediatric tumors
por: Ciceri, Sara, et al.
Publicado: (2022)

Further Delineation of the Spectrum of XMEN Disease in Six Chinese Pediatric Patients
por: Peng, Xiaomin, et al.
Publicado: (2022)

Differential Infiltration of Immune Cells Driven by Tumor Heterogeneity Reveals Two Immune Subtypes in Lung Adenocarcinoma
por: Wang, Liqiang, et al.
Publicado: (2022)

Delineating the intra-patient heterogeneity of molecular alterations in treatment-naïve colorectal cancer with peritoneal carcinomatosis
por: Siesing, Christina, et al.
Publicado: (2022)

Intra-Tumor Heterogeneity Revealed by Mass Spectrometry Imaging Is Associated with the Prognosis of Breast Cancer
por: Gawin, Marta, et al.
Publicado: (2021)

Dynamic Emergence of Observed and Hidden Intra-tumor Heterogeneity
por: Raynaud, Franck, et al.
Publicado: (2019)

epihet for intra-tumoral epigenetic heterogeneity analysis and visualization
por: Chen, Xiaowen, et al.
Publicado: (2021)

Simulating the Dynamic Intra-Tumor Heterogeneity and Therapeutic Responses
por: Liu, Yongjing, et al.
Publicado: (2022)

Triple negative breast cancer: Immunogenicity, tumor microenvironment, and immunotherapy
por: Loizides, Sotiris, et al.
Publicado: (2023)

Mutant-Allele Tumor Heterogeneity, a Favorable Biomarker to Assess Intra-Tumor Heterogeneity, in Advanced Lung Adenocarcinoma
por: Wu, Xiaoxuan, et al.
Publicado: (2022)

Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification
por: Ng, Charlotte KY, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_40qrmtvcsrp6v047si1t1gjfa2