DNA and histones impair the mechanical stability and lytic susceptibility of fibrin formed by staphylocoagulase

BACKGROUND: Staphylocoagulase (SCG) is a virulence factor of Staphylococcus aureus, one of the most lethal pathogens of our times. The complex of SCG with prothrombin (SCG/ProT) can clot fibrinogen, and SCG/ProT-induced fibrin and plasma clots have been described to show decreased mechanical and lyt...

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Detalles Bibliográficos
Autores principales: Komorowicz, Erzsébet, Farkas, Veronika J., Szabó, László, Cherrington, Sophie, Thelwell, Craig, Kolev, Krasimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470048/
https://www.ncbi.nlm.nih.gov/pubmed/37662916
http://dx.doi.org/10.3389/fimmu.2023.1233128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470048/
https://www.ncbi.nlm.nih.gov/pubmed/37662916
http://dx.doi.org/10.3389/fimmu.2023.1233128

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