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Identification of distinct impacts of CovS inactivation on the transcriptome of acapsular group A streptococci
Group A streptococcal (GAS) strains causing severe, invasive infections often have mutations in the control of virulence two-component regulatory system (CovRS) which represses capsule production, and high-level capsule production is considered critical to the GAS hypervirulent phenotype. Additional...
Autores principales: | DebRoy, Sruti, Shropshire, William C., Vega, Luis, Tran, Chau, Horstmann, Nicola, Mukherjee, Piyali, Selvaraj-Anand, Selvalakshmi, Tran, Truc T., Bremer, Jordan, Gohel, Marc, Arias, Cesar A., Flores, Anthony R., Shelburne, Samuel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470059/ https://www.ncbi.nlm.nih.gov/pubmed/37358280 http://dx.doi.org/10.1128/msystems.00227-23 |
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