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Human T cells loaded with superparamagnetic iron oxide nanoparticles retain antigen-specific TCR functionality

BACKGROUND: Immunotherapy of cancer is an emerging field with the potential to improve long-term survival. Thus far, adoptive transfer of tumor-specific T cells represents an effective treatment option for tumors of the hematological system such as lymphoma, leukemia or myeloma. However, in solid tu...

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Detalles Bibliográficos
Autores principales: Pfister, Felix, Dörrie, Jan, Schaft, Niels, Buchele, Vera, Unterweger, Harald, Carnell, Lucas R., Schreier, Patrick, Stein, Rene, Kubánková, Markéta, Guck, Jochen, Hackstein, Holger, Alexiou, Christoph, Janko, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470061/
https://www.ncbi.nlm.nih.gov/pubmed/37662937
http://dx.doi.org/10.3389/fimmu.2023.1223695