CAR-T cells targeting CD38 and LMP1 exhibit robust antitumour activity against NK/T cell lymphoma

BACKGROUND: Natural killer/T cell lymphoma (NKTCL) is an aggressive lymphoma with a poor prognosis. Chimeric antigen receptor-transduced T (CAR-T) cell therapy has become a promising immunotherapeutic strategy against haematologic malignancies. METHODS: In this study, four CAR-T cell lines (CD38-CAR...

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Detalles Bibliográficos
Autores principales: Li, Hongwen, Song, Wenting, Wu, Jiazhuo, Shi, Zhuangzhuang, Gao, Yuyang, Li, Jiwei, Han, Lijuan, Zhang, Jianxiang, Li, Zhaoming, Li, Yong, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470138/
https://www.ncbi.nlm.nih.gov/pubmed/37649020
http://dx.doi.org/10.1186/s12916-023-03040-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470138/
https://www.ncbi.nlm.nih.gov/pubmed/37649020
http://dx.doi.org/10.1186/s12916-023-03040-0

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