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Synergistic anti-tumour activity of sorafenib in combination with pegylated resveratrol is mediated by Akt/mTOR/p70S6k-4EBP-1 and c-Raf7MEK/ERK signaling pathways

INTRODUCTION: To investigate the inhibitory effect of sorafenib combined with PEGylated resveratrol on renal cell carcinoma (RCC) and its potential mechanism. METHODS: MTT assay was used to detect the inhibitory effects of PEGylated resveratrol and sorafenib alone or combination on proliferation of...

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Detalles Bibliográficos
Autores principales:	Wang, Ligang, Wu, Hao, Wang, Ying, Xu, Songcheng, Yang, Chen, Zhang, Tingting, Liu, Yang, Wang, Fuwei, Chen, Weinan, Li, Jianchun, Sun, Litao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470186/ https://www.ncbi.nlm.nih.gov/pubmed/37664741 http://dx.doi.org/10.1016/j.heliyon.2023.e19154

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