DnaQ mediates directional spacer acquisition in the CRISPR-Cas system by a time-dependent mechanism

In the spacer acquisition stage of CRISPR-Cas immunity, spacer orientation and protospacer adjacent motif (PAM) removal are two prerequisites for functional spacer integration. Cas4 has been implicated in both processing the prespacer and determining the spacer orientation. In Cas4-lacking systems,...

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Detalles Bibliográficos
Autores principales: Tang, Dongmei, Jia, Tingting, Luo, Yongbo, Mou, Biqin, Cheng, Jie, Qi, Shiqian, Yao, Shaohua, Su, Zhaoming, Yu, Yamei, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470216/
https://www.ncbi.nlm.nih.gov/pubmed/37663930
http://dx.doi.org/10.1016/j.xinn.2023.100495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470216/
https://www.ncbi.nlm.nih.gov/pubmed/37663930
http://dx.doi.org/10.1016/j.xinn.2023.100495

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