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Clinical and Genomic Factors Associated with Greater Tumor Mutational Burden in Prostate Cancer
Tumor mutational burden (TMB) is a biomarker that predicts response to immune checkpoint inhibitor therapy. We currently lack a comprehensive understanding of how genomic and clinical factors correlate with TMB. We used a clinicogenomic database to assess independent predictors of TMB levels. The st...
Autores principales: | Hougen, Helen Y., Graf, Ryon P., Li, Gerald, Quintanilha, Julia C.F., Lin, Douglas I., Ross, Jeffrey S., Punnen, Sanoj, Mahal, Brandon A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470357/ https://www.ncbi.nlm.nih.gov/pubmed/37662703 http://dx.doi.org/10.1016/j.euros.2023.08.001 |
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