Case report: Granzyme-B expression by T- and B- cells during severe AQP4-positive Neuromyelitis Optica spectrum disorder with fatal venous thromboembolism outcome

BACKGROUND: The expression of serine protease granzyme-B (GzmB) by circulating CD8(+) T lymphocytes has been recently suggested as a biomarker for poor immunotherapy response and severe disability in patients with Neuromyelitis Optica spectrum disorders (NMOSD). In parallel, venous thromboembolism (...

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Detalles Bibliográficos
Autores principales: Boldrini, Vinícius Oliveira, Brito, Mariana Rabelo, Quintiliano, Raphael Patrício Silva, Scárdua Silva, Lucas, Yasuda, Clarissa Lin, Cendes, Fernando, Farias, Alessandro Santos, Damasceno, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470460/
https://www.ncbi.nlm.nih.gov/pubmed/37662034
http://dx.doi.org/10.3389/fneur.2023.1208977

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