Modulation of the functional interfaces between retroviral intasomes and the human nucleosome

Infection by retroviruses as HIV-1 requires the stable integration of their genome into the host cells. This process needs the formation of integrase (IN)-viral DNA complexes, called intasomes, and their interaction with the target DNA wrapped around nucleosomes within cell chromatin. To provide new...

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Detalles Bibliográficos
Autores principales: Mauro, E., Lapaillerie, D., Tumiotto, C., Charlier, C., Martins, F., Sousa, S. F., Métifiot, M., Weigel, P., Yamatsugu, K., Kanai, M., Munier-Lehmann, H., Richetta, C., Maisch, M., Dutrieux, J., Batisse, J., Ruff, M., Delelis, O., Lesbats, P., Parissi, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470491/
https://www.ncbi.nlm.nih.gov/pubmed/37382440
http://dx.doi.org/10.1128/mbio.01083-23

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