The largest HIV-1-infected T cell clones in children on long-term combination antiretroviral therapy contain solo LTRs

Combination antiretroviral therapy (cART) suppresses viral replication but does not cure HIV infection because a reservoir of infectious (intact) HIV proviruses persists in long-lived CD4+T cells. However, a large majority (>95%) of HIV-infected cells that persist on effective cART carry defectiv...

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Detalles Bibliográficos
Autores principales: Botha, Johannes C., Demirov, Dimiter, Gordijn, Carli, Katusiime, Mary Grace, Bale, Michael J., Wu, Xiaolin, Wells, Daria, Hughes, Stephen H., Cotton, Mark F., Mellors, John W., Kearney, Mary F., van Zyl, Gert U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470503/
https://www.ncbi.nlm.nih.gov/pubmed/37530525
http://dx.doi.org/10.1128/mbio.01116-23

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