Optimized quantification of intra-host viral diversity in SARS-CoV-2 and influenza virus sequence data

High error rates of viral RNA-dependent RNA polymerases lead to diverse intra-host viral populations during infection. Errors made during replication that are not strongly deleterious to the virus can lead to the generation of minority variants. However, accurate detection of minority variants in vi...

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Detalles Bibliográficos
Autores principales: Roder, A. E., Johnson, K. E. E., Knoll, M., Khalfan, M., Wang, B., Schultz-Cherry, S., Banakis, S., Kreitman, A., Mederos, C., Youn, J.-H., Mercado, R., Wang, W., Chung, M., Ruchnewitz, D., Samanovic, M. I., Mulligan, M. J., Lässig, M., Luksza, M., Das, S., Gresham, D., Ghedin, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470513/
https://www.ncbi.nlm.nih.gov/pubmed/37389439
http://dx.doi.org/10.1128/mbio.01046-23

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