CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function

Invasive aspergillosis is one of the most serious clinical invasive fungal infections, resulting in a high case fatality rate among immunocompromised patients. The disease is caused by saprophytic molds in the genus Aspergillus, including Aspergillus fumigatus, the most significant pathogenic specie...

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Detalles Bibliográficos
Autores principales: Han, Xu, D'Angelo, Cecilia, Otamendi, Ainara, Cifuente, Javier O., de Astigarraga, Elisa, Ochoa-Lizarralde, Borja, Grininger, Martin, Routier, Francoise H., Guerin, Marcelo E., Fuehring, Jana, Etxebeste, Oier, Connell, Sean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470519/
https://www.ncbi.nlm.nih.gov/pubmed/37409813
http://dx.doi.org/10.1128/mbio.00414-23

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