Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations

The inflammatory bowel diseases (IBD) occur in genetically susceptible individuals who mount inappropriate immune responses to their microbiota leading to chronic intestinal inflammation. Whereas IBD clinical presentation is well described, how interactions between microbiota and host genotype impac...

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Detalles Bibliográficos
Autores principales: Kelly, Cecelia, Jawahar, Jayanth, Davey, Lauren, Everitt, Jeffrey I., Galanko, Joseph A., Anderson, Chelsea, Avendano, Jonathan E., McCann, Jessica R., Sartor, R. Balfour, Valdivia, Raphael H., Rawls, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470520/
https://www.ncbi.nlm.nih.gov/pubmed/37526424
http://dx.doi.org/10.1128/mbio.01504-23

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