RecJ3/4-aRNase J form a Ubl-associated nuclease complex functioning in survival against DNA damage in Haloferax volcanii

Nucleases are strictly regulated and often localized in the cell to avoid the uncontrolled degradation of DNA and RNA. Here, a new type of nuclease complex, composed of RecJ3, RecJ4, and aRNase J, was identified through its ATP-dependent association with the ubiquitin-like SAMP1 and AAA-ATPase Cdc48...

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Detalles Bibliográficos
Autores principales: Jia, Huiyong, Dantuluri, Swathi, Margulies, Shae, Smith, Victoria, Lever, Rebecca, Allers, Thorsten, Koh, Jin, Chen, Sixue, Maupin-Furlow, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470531/
https://www.ncbi.nlm.nih.gov/pubmed/37458473
http://dx.doi.org/10.1128/mbio.00852-23

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