Pathogen-specific structural features of Candida albicans Ras1 activation complex: uncovering new antifungal drug targets

An important feature associated with Candida albicans pathogenicity is its ability to switch between yeast and hyphal forms, a process in which CaRas1 plays a key role. CaRas1 is activated by the guanine nucleotide exchange factor (GEF) CaCdc25, triggering hyphal growth-related signaling pathways th...

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Detalles Bibliográficos
Autores principales: Manso, José A., Carabias, Arturo, Sárkány, Zsuzsa, de Pereda, José M., Pereira, Pedro José Barbosa, Macedo-Ribeiro, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470544/
https://www.ncbi.nlm.nih.gov/pubmed/37526476
http://dx.doi.org/10.1128/mbio.00638-23

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