Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulence

Identification of the mechanisms of viral evasion from human antibodies is crucial both for understanding viral pathogenesis and for designing effective vaccines. Here we show in cell cultures that an N-glycan shield on the herpes simplex virus 1 (HSV-1) envelope glycoprotein B (gB) mediated evasion...

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Detalles Bibliográficos
Autores principales: Fukui, Ayano, Maruzuru, Yuhei, Ohno, Shiho, Nobe, Moeka, Iwata, Shuji, Takeshima, Kosuke, Koyanagi, Naoto, Kato, Akihisa, Kitazume, Shinobu, Yamaguchi, Yoshiki, Kawaguchi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470582/
https://www.ncbi.nlm.nih.gov/pubmed/37366623
http://dx.doi.org/10.1128/mbio.00992-23

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