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Small molecules restore azole activity against drug-tolerant and drug-resistant Candida isolates

Each year, fungi cause more than 1.5 billion infections worldwide and have a devastating impact on human health, particularly in immunocompromised individuals or patients in intensive care units. The limited antifungal arsenal and emerging multidrug-resistant species necessitate the development of n...

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Detalles Bibliográficos
Autores principales: Alabi, Philip E., Gautier, Cécile, Murphy, Thomas P., Gu, Xilin, Lepas, Mathieu, Aimanianda, Vishukumar, Sello, Jason K., Ene, Iuliana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470600/
https://www.ncbi.nlm.nih.gov/pubmed/37326546
http://dx.doi.org/10.1128/mbio.00479-23